COVID-19 has drastically impacted the healthcare system across the continuum of care. View the resources below, submitted by healthcare providers who are managing COVID-19 patients, to help you and your organization get ahead of the COVID-19 pandemic.
Have a resource to share with other healthcare providers? Please submit it via email to info@sepsisinstitute.org.
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Forum Discussion
Join the Sepsis Coordinator Network to take part in a discussion with your peers (healthcare providers) about COVID-19.
Medical Journal Articles
| Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine January 13, 2021 The New England Journal of Medicine |
| International Impact of COVID-19 on the Diagnosis of Heart Disease January 2021 Journal of the American College of Cardiology |
| Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 January 11, 2021 |
| Genetic Variants of SARS-CoV-2 May Lead to False Negative Results with Molecular Tests for Detection of SARS-CoV-2 - Letter to Clinical Laboratory Staff and Health Care Providers January 8, 2021 FDA |
| Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study January 8, 2021 The Lancet |
| Assessment of Day-7 Postexposure Testing of Asymptomatic Contacts of COVID-19 Patients to Evaluate Early Release from Quarantine — Vermont, May–November 2020 January 8, 2021 CDC |
| SARS-CoV-2 Transmission From People Without COVID-19 Symptoms January 7, 2021 JAMA |
| Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report January 7, 2021 MedRxiv |
| Comparison of Out-of-Hospital Cardiac Arrests and Fatalities in the Metro Detroit Area During the COVID-19 Pandemic With Previous-Year Events January 6, 2021 JAMA |
| Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults January 6, 2021 The New England Journal of Medicine |
| Impact of COVID‐19 on inpatient referral of acute heart failure: a single‐centre experience from the south‐west of the UK January 6 ESC Heart Failure |
| Persistent Poor Health Post-COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity January 6, 2021 Annals of the American Thoracic Society |
| Umbilical cord mesenchymal stem cells for COVID‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial January 5, 2021 Stem Cells Translational Medicine |
| Estimation of US SARS-CoV-2 Infections, Symptomatic Infections, Hospitalizations, and Deaths Using Seroprevalence Surveys January 5, 2021 JAMA |
| Risk Factors Associated With All-Cause 30-Day Mortality in Nursing Home Residents With COVID-19 January 4, 2021 JAMA |
| Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine December 30, 2020 The New England Journal of Medicine |
| Impact of corticosteroids and immunosuppressive therapies on symptomatic SARS-CoV-2 infection in a large cohort of patients with chronic inflammatory arthritis December 30, 2020 Arthritis Research and Therapy |
| Factors Associated with Positive SARS-CoV-2 Test Results in Outpatient Health Facilities and Emergency Departments Among Children and Adolescents Aged <18 Years — Mississippi, September–November 2020 December 18 CDC |
| Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study December 17 The Lancet Respiratory Medicine |
| Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia December 17 The New England Journal of Medicine |
| Racial Bias in Pulse Oximetry Measurement December 17 The New England Journal of Medicine |
| Patient-Reported Experiences of Discrimination in the US Health Care System December 15 JAMA |
| Readmission and Death After Initial Hospital Discharge Among Patients With COVID-19 in a Large Multihospital System December 14, 2021 JAMA |
| Household Transmission of SARS-CoV-2 A Systematic Review and Meta-analysis December 14 JAMA |
| Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 December 11 The New England Journal of Medicine |
| Universal screening for SARS-CoV-2 infection among pregnant women at Elmhurst Hospital Center, Queens, New York December 10 PLOS One |
| Children and COVID-19: State-Level Data Report December 10 American Academy of Pediatrics |
| Assessment of Machine Learning to Estimate the Individual Treatment Effect of Corticosteroids in Septic Shock Dec 10 JAMA |
| Risk Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19 December 10 JAMA |
| Assessment of Racial/Ethnic Disparities in Hospitalization and Mortality in Patients With COVID-19 in New York City December 4, 2020 JAMA |
| Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer December 1 The New England Journal of Medicine |
| Antibody Cocktail for COVID-19 Gets Emergency Use Authorization November 30 Infectious Disease Advisor |
| Remdesivir Superior to Placebo in Hospitalized Patients With COVID-19 November 25 Infectious Disease Advisor |
| Association Between ABO and Rh Blood Groups and SARS-CoV-2 Infection or Severe COVID-19 Illness November 24, 2020 Annals of Internal Medicine |
| Surviving COVID-19 After Hospital Discharge: Symptom, Functional, and Adverse Outcomes of Home Health Recipients November 24 Annals of Internal Medicine |
| A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia November 24 The New England Journal of Medicine |
| Risk factors and outcomes of hospitalized patients with severe COVID-19 and secondary bloodstream infections: A multicenter, case-control study November 20, 2020 Clinical Infectious Diseases |
| Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia November 20, 2020 Journal of Thrombosis and Haemostasis (JTH) |
| SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis November 19 The Lancet |
| SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells November 13 Cell Metabolism |
| Clinical Outcomes From COVID-19 Infections Poorer Among Patients with Substance Use Disorders November 16 Psychiatric Services in Advance |
| Low incidence of severe gastrointestinal complications in COVID-19 patients admitted to the intensive care unit: a large, multi-center study November 12 Gastroenterology |
| Remdesivir for the Treatment of Covid-19 — Final Report November 5 The New England Journal of Medicine |
| Identifying patients with symptoms suspicious for COVID-19 at elevated risk of adverse events: The COVAS score November 4 American Journal of Emergency Medicine |
| Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship November 2 European Journal of Clinical Microbiology & Infectious Diseases |
| FDA Approves First Treatment for COVID-19 October 22 FDA |
| CDC redefines COVID-19 close contact, adds brief encounters October 21 AP News |
| Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia October 20 JAMA |
| Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App October 21 |
| Excess Deaths Associated with COVID-19, by Age and Race and Ethnicity — United States, January 26–October 3, 2020 October 20 CDC |
| Race, Ethnicity, and Age Trends in Persons Who Died from COVID-19 — United States, May–August 2020 October 16 CDC |
| Large Meta-analysis Digs Into Obesity’s COVID-19 Risks October 15 JAMA |
| A Point-Based Risk Calculator Predicting Mortality in Patients That Developed Postoperative Sepsis Journal of Intensive Care Medicine October 12 |
| Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019 October 12 CHEST |
| Genomic evidence for reinfection with SARS-CoV-2: a case study October 12 The Lancet |
| Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March–August 2020 October 9 CDC |
| Transmission Dynamics by Age Group in COVID-19 Hotspot Counties — United States, April–September 2020 October 9 CDC |
| Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study October 8 The Lancet |
| Most Coronavirus-Positive Cancer Patients Are Asymptomatic, Says Study October 7 Cancer Therapy Advisor |
Guideline Documents
Review guidance from countries and hospital systems that are responding to COVID-19.
Training to Help Staff Be Critical Care Capable
Resources Pages
View additional resources from organizations and societies.
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