COVID-19 has drastically impacted the healthcare system across the continuum of care. View the resources below, submitted by healthcare providers who are managing COVID-19 patients, to help you and your organization get ahead of the COVID-19 pandemic.
Have a resource to share with other healthcare providers? Please submit it via email to info@sepsisinstitute.org.
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Forum Discussion
Join the Sepsis Alliance Clinical Community to take part in a discussion with your peers (healthcare providers) about COVID-19.
Medical Journal Articles
| Association of Simulated COVID-19 Vaccination and Nonpharmaceutical Interventions With Infections, Hospitalizations, and Mortality June 1, 2021 JAMA |
| Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study THE LANCET June 1, 2021 |
| Same-day SARS-CoV-2 antigen test screening in an indoor mass-gathering live music event: a randomized controlled trial May 27, 2021 |
| Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection Results From the Big Ten COVID-19 Cardiac Registry May 27, 2021 JAMA |
| Association of Circulating Sex Hormones With Inflammation and Disease Severity in Patients With COVID-19 May 25, 2021 JAMA |
| Absence of Humoral Response After Two-Dose SARS-CoV-2 Messenger RNA Vaccination in Patients With Rheumatic and Musculoskeletal Diseases: A Case Series May 25, 2021 Annals of Internal Medicine |
| Effectiveness of Tocilizumab in Patients Hospitalized With COVID-19 A Follow-up of the CORIMUNO-TOCI-1 Randomized Clinical Trial May 24, 2021 JAMA |
| Admission respiratory status predicts mortality in COVID-19 May 24, 2021 Influenza and Other Respiratory Viruses |
| Antibody Cocktail Reduced Poor Outcomes in High-Risk COVID May 18, 2021 ATS Meeting MEDPAGE TODAY |
| Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial May 14, 2021 THE LANCET |
| Mask adherence and rate of COVID-19 across the United States April 14, 2021 PLOS ONE |
| Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients April 13, 2021 British Journal of Sports Medicine |
| Cases of Cerebral Venous Sinus Thrombosis with Thrombocytopenia after Receipt of the Johnson & Johnson COVID-19 Vaccine April 13, 2021 CDC |
| Emergency Department Visits for COVID-19 by Race and Ethnicity — 13 States, October–December 2020 April 12, 2021 CDC |
| Trends in Racial and Ethnic Disparities in COVID-19 Hospitalizations, by Region — United States, March–December 2020 April 12, 2021 |
| Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial April 9, 2021 THE LANCET |
| Mortality Among US Patients Hospitalized With SARS-CoV-2 Infection in 2020 April 8, 2021 JAMA |
| Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers April 7, 2021 JAMA |
| Association of Human Mobility Restrictions and Race/Ethnicity–Based, Sex-Based, and Income-Based Factors with Inequities in Well-being During the COVID-19 Pandemic in the United States April 7, 2021 JAMA |
| Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians April 6, 2021 Annals of Internal Medicine |
| Trends in Geographic and Temporal Distribution of US Children With Multisystem Inflammatory Syndrome During the COVID-19 Pandemic April 6, 2021 JAMA Pediatrics |
| 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records April 6, 2021 THE LANCET |
| Greater Frequency of Stroke in Men With COVID-19 and High Comorbidity Burden April 6, 2021 Neurology Advisor |
| Association of Sociodemographic Factors and Blood Group Type With Risk of COVID-19 in a US Population April 5, 2021 JAMA |
| Incidence of 30-Day Venous Thromboembolism in Adults Tested for SARS-CoV-2 Infection in an Integrated Health Care System in Northern California April 5, 2021 JAMA |
| Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021 April 2, 2021 JAMA |
| Counties with High COVID-19 Incidence and Relatively Large Racial and Ethnic Minority Populations — United States, April 1–December 22, 2020 April 2, 2021 CDC |
| The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients April 1, 2021 Critical Care Medicine |
| Use of Biomarkers to Identify Acute Kidney Injury to Help Detect Sepsis in Patients With Infection April 1, 2021 Critical Care Medicine |
| Aspirin Use Is Associated with Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients with Coronavirus Disease 2019 April 2021 Anesthesia & Analgesia |
| COVID-19 illness in relation to sleep and burnout March 22, 2021 BMJ Nutrition, Prevention, & Health |
| Transmissibility and transmission of respiratory viruses March 22, 2021 Nature |
| Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis March 19, 2021 JAMA |
| Inequities in Technology Contribute to Disparities in COVID-19 Vaccine Distribution March 19, 2021 |
| US Hospital Capacity Managers’ Experiences and Concerns Regarding Preparedness for Seasonal Influenza and Influenza-like Illness March 19, 2021 JAMA |
| Assessment of the Appropriateness of Antimicrobial Use in US Hospitals March 18, 2021 JAMA |
| Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit The INSPIRATION Randomized Clinical Trial March 18, 2021 JAMA |
| Outcomes for Patients Following Hospitalization for COVID-19 March 17, 2021 JAMA |
| Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study March 17, 2021 The Lancet |
| Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients March 15, 2021 JAMA |
| Experiences of Latinx Individuals Hospitalized for COVID-19 A Qualitative Study March 11, 2021 JAMA |
| Risk Factors Associated With SARS-CoV-2 Seropositivity Among US Health Care Personnel March 10, 2021 JAMA |
| The Devastating Impact of Covid-19 on Individuals with Intellectual Disabilities in the United States March 5, 2021 NEJM Catalyst |
| Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome March 5, 2021 JAMA |
| Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms March 4, 2021 Gastroenterology |
| Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19 March 4, 2021 |
| Acute kidney injury in pediatric patients hospitalized with acute COVID-19 and Multisystem Inflammatory Syndrome in Children associated with COVID-19 March 3, 2021 Kidney International |
| Coronavirus Disease 2019 Hospitalizations Attributable to Cardiometabolic Conditions in the United States: A Comparative Risk Assessment Analysis February 25, 2021 Journal of the American Heart Association |
| Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection February 24, 2021 JAMA |
| Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 February 24, 2021 JAMA |
| BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting February 24, 2021 The New England Journal of Medicine |
| The COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of the Bamlanivimab Plus Etesevimab Combination for the Treatment of COVID-19 Last Updated: February 23, 2021 NIH COVID-19 Treatment Guidelines |
| Impact of the Influenza Vaccine on COVID-19 Infection Rates and Severity February 22, 2021 American Journal of Infection Control |
| Sequelae in Adults at 6 Months After COVID-19 Infection February 19, 2021 JAMA |
| Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19 February 17, 2021 JAMA |
| Thresholds of Glycemia and the Outcomes of COVID-19 Complicated With Diabetes: A Retrospective Exploratory Study Using Continuous Glucose Monitoring February 11, 2021 Diabetes Care |
| Asthma and risk of infection, hospitalisation, ICU admission and mortality from COVID-19: Systematic review and meta-analysis February 5, 2021 Journal of Asthma |
| Bacterial superinfections among persons with coronavirus disease 2019:A comprehensive review of data from postmortem studies February 4, 2021 Open Forum Infectious Diseases |
| Clinical Course of Cancer Patients With COVID-19: A Retrospective Cohort Study November 2, 2020/February 2021 JNCI Cancer Spectrum |
| Geographic Variation in Racial Disparities in Mortality from Influenza and Pneumonia in the US in the Pre-COVID-19 Era January 1, 2021 CHEST |
| Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection February 12, 2021 JAMA |
| Recommended Adult Immunization Schedule, United States, 2021* February 11, 2021 Annals of Internal Medicine |
| COVID Clot Prevention: Hit It Early - Observational study supports guidelines February 11, 2021 Infectious Disease |
| Translating Post-Sepsis Care to Post-COVID Care: The Case for a Virtual Recovery Program February 10, 2021 Annals of the American Thoracic Society |
| Factors Associated With Racial Differences in Deaths Among Nursing Home Residents With COVID-19 Infection in the US February 10, 2021 JAMA |
| Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area February 10, 2021 CMAJ (Canadian Medical Association Journal) |
| Coronavirus (COVID-19) Update: FDA Authorizes Monoclonal Antibodies for Treatment of COVID-19 February 9, 2021 FDA |
| COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US February 9, 2021 Alzheimer’s & Dementia |
Guideline Documents
Review guidance from countries and hospital systems that are responding to COVID-19.
Training to Help Staff Be Critical Care Capable
Resources Pages
View additional resources from organizations and societies.
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