COVID-19 and Sepsis

COVID-19 has drastically impacted the healthcare system across the continuum of care. View the resources below, submitted by healthcare providers who are managing COVID-19 patients, to help you and your organization get ahead of the COVID-19 pandemic.

Have a resource to share with other healthcare providers? Please submit it via email to info@sepsisinstitute.org.

Webinars

May 28, 2020 at 2 pm ET: COVID-19: Current Treatment Guidelines for the Critically Ill

COVID-19 and Sepsis (Recorded 3/25)

COVID-19, Sepsis, and Home Health Care (Recorded 4/23)

Mobilizing Telehealth During the COVID-19 Pandemic (Recorded 5/5)

Forum Discussion

Join the Sepsis Coordinator Network to take part in a discussion with your peers (healthcare providers) about COVID-19.

Medical Journal Articles

Novel viruses, old data, and basic principles: how to save lives and avoid harm amid the unknown May 21 The Lancet
High Incidence of Thromboembolic Events in Patients Who Died of COVID-19 May 21
The immunology of COVID-19: is immune modulation an option for treatment? May 20 The Lancet
Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study May 19 The Lancet
Anticoagulant Treatment Is Associated With Decreased Mortality in Severe Coronavirus Disease 2019 Patients With Coagulopathy May 18 Journal of Thrombosis and Haemostasis
Elevated Level of C Reactive Protein May Predict Risk for Worsening COVID-19 May 15 Infectious Diseases
Kawasaki-like disease: emerging complication during the COVID-19 pandemic May 13 The Lancet
A wake-up call: COVID-19 and its impact on children's health and wellbeing May 12 The Lancet
Clinical Characteristics of 5 COVID-19 Cases With Non-respiratory Symptoms as the First Manifestation in Children May 12 frontiers in Pediatrics
Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modeling study May 12 The Lancet
Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis May 12 The Lancet
Association Between IV Thiamine and Mortality in Patients with Septic Shock May 11 Critical Care Medicine
Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units May 11 JAMA Pediatrics
New York State Department of Health (NYS DOH) Bureau of Communicable Disease Control (BCDC) Health advisory: Pediatric multi-system inflammatory syndrome potentially associated with coronavirus disease (COVID-19) in children May 6
Hyperinflammatory shock in children during COVID-19 pandemic May 7 The Lancet
High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study May 4 Intensive Care Medicine
Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel May 3 International Journal of Stroke
Timing of immune response to COVID-19 may contribute to disease severity May 1 Science Daily
COVID-19: don’t neglect antimicrobial stewardship principles! April 30 Clinical Microbiology and Infection
Children with Covid-19 in Pediatric Emergency Departments in Italy (description of 100 children with COVID-19 in pediatric ER) May 1 The New England Journal of Medicine
Clinical Characteristics of Coronavirus Disease 2019 in China April 30 The New England Journal of Medicine
The Center to Advance Palliative Care (CAPC) COVID-19 Response Resources
Advance Care Planning During a Crisis Key Information for Nursing Facility Staff
Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19: A Cohort Study American Journal of Respiratory Critical Care April 29
The Clinical Presentation and Immunology of Viral Pneumonia and Implications for Management of Coronavirus Disease 2019 Critical Care Explorations April
Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs April 29 JAMA
Moving Personal Protective Equipment Into the Community Face Shields and Containment of COVID-19 April 29 JAMA
Effective treatment of severe COVID-19 patients with tocilizumab April 29 Proceedings from the National Academy of Sciences of the United States of America
ACEP COVID-19 Field Guide Telehealth and Tele-Triage updated April 29 American College of Emergency Physicians
COVID-19 and Multi-Organ Response April 28 Current Problems in Cardiology
Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young April 28 The New England Journal of Medicine
A Step-by-Step Guide to Preventing PPE-Related Skin Damage April 28
Seniors With COVID-19 Show Unusual Symptoms, Doctors Say April 27
Infectious Diseases Society of America Guidelines on Infection Prevention in Patients with Suspected or Known COVID-19 April 27
'Hospital at Home' May Boost COVID-19 Inpatient Capacity April 26
Management of COVID-19 Respiratory Distress April 24 JAMA
Characteristics of Hospitalized Adults With COVID-19 in an Integrated Health Care System in California April 24 JAMA
Mild or Moderate Covid-19 April 24 The New England Journal of Medicine
Asymptomatic Transmission, the Achilles’ Heel of Current Strategies to Control Covid-19 April 24 The New England Journal of Medicine
FDA Drug Safety Communication FDA cautions against use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial due to risk of heart rhythm problems Does not affect FDA-approved uses for malaria, lupus, and rheumatoid arthritis April 24
Coronavirus (COVID-19) Update: Ventilatory Management for COVID-Related Respiratory Failure April 24 JAMA
Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis April 23 The Journal of Infection
Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2 April 22 Journal of Allergy and Clinical Immunology
Thrombosis and COVID-19: FAQs For Current Practice Apr 22, 2020 Cardiology Magazine
Late-Onset Neonatal Sepsis in a Patient with Covid-19 April 22 (New England Journal of Medicine)
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area April 22 JAMA Network
ACC, SCAI, ACEP Release Consensus Statement on Management of AMI Patients During COVID-19 April 20
SARS-CoV-2 and Viral Sepsis: Observations and Hypotheses - April 17 (The Lancet)
Joint Statement: Roadmap for Resuming Elective Surgery after COVID-19 Pandemic April 17, 2020
Neurologic Features in Severe SARS-CoV-2 Infection April 15 New England Journal of Medicine
COVID-19 pneumonia: different respiratory treatments for different phenotypes? April 14 Intensive Care Medicine
SMFM and the Society for Obstetric Anesthesia and Perinatology (SOAP) revise Labor and Delivery COVID-19 Considerations (April 14, 2020; updated from an earlier version on March 27, 2020)
Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children, The Pediatric Infectious Disease Journal May 2020
Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020, CDC April 10, 2020
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China April 10 JAMA
COVID-19 in Children in the United States, NEJM Journal Watch April 8, 2020
Coronavirus (COVID-19) Update: Reusing Face Masks and N95 Respirators [audio] April 8
JAMA Pediatrics - Coronavirus Disease 2019 and Children: What Pediatric Health Care Clinicians Need to Know
Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy April 6
Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 March 23 JAMA
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study March 9 Lancet
COVID-19 and Sepsis Coding: New Guidelines