COVID-19 has drastically impacted the healthcare system across the continuum of care. View the resources below, submitted by healthcare providers who are managing COVID-19 patients, to help you and your organization get ahead of the COVID-19 pandemic.

Have a resource to share with other healthcare providers? Please submit it via email to info@sepsisinstitute.org.

Webinars

Register for upcoming live events or view recordings from past webinars on COVID-19.

COVID-19 and Sepsis (Recorded 3/25)
COVID-19, Sepsis, and Home Health Care (Recorded 4/23)
Mobilizing Telehealth During the COVID-19 Pandemic (Recorded 5/5)
COVID-19: Current Treatment Guidelines for the Critically Ill (Recorded 5/28)
Live Webinar: Surviving COVID-19: The Path to Optimal Recovery - 7/9

Forum Discussion

Join the Sepsis Coordinator Network to take part in a discussion with your peers (healthcare providers) about COVID-19.

Medical Journal Articles

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine January 13, 2021 The New England Journal of Medicine
International Impact of COVID-19 on the Diagnosis of Heart Disease January 2021 Journal of the American College of Cardiology
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 January 11, 2021 
Genetic Variants of SARS-CoV-2 May Lead to False Negative Results with Molecular Tests for Detection of SARS-CoV-2 - Letter to Clinical Laboratory Staff and Health Care Providers January 8, 2021 FDA
Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study January 8, 2021 The Lancet
Assessment of Day-7 Postexposure Testing of Asymptomatic Contacts of COVID-19 Patients to Evaluate Early Release from Quarantine — Vermont, May–November 2020 January 8, 2021 CDC
SARS-CoV-2 Transmission From People Without COVID-19 Symptoms January 7, 2021 JAMA
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report January 7, 2021 MedRxiv
Comparison of Out-of-Hospital Cardiac Arrests and Fatalities in the Metro Detroit Area During the COVID-19 Pandemic With Previous-Year Events January 6, 2021 JAMA
Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults January 6, 2021 The New England Journal of Medicine
Impact of COVID‐19 on inpatient referral of acute heart failure: a single‐centre experience from the south‐west of the UK January 6 ESC Heart Failure
Persistent Poor Health Post-COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity January 6, 2021 Annals of the American Thoracic Society
Umbilical cord mesenchymal stem cells for COVID‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial January 5, 2021 Stem Cells Translational Medicine
Estimation of US SARS-CoV-2 Infections, Symptomatic Infections, Hospitalizations, and Deaths Using Seroprevalence Surveys January 5, 2021 JAMA
Risk Factors Associated With All-Cause 30-Day Mortality in Nursing Home Residents With COVID-19 January 4, 2021 JAMA
Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine December 30, 2020 The New England Journal of Medicine
Impact of corticosteroids and immunosuppressive therapies on symptomatic SARS-CoV-2 infection in a large cohort of patients with chronic inflammatory arthritis December 30, 2020 Arthritis Research and Therapy
Factors Associated with Positive SARS-CoV-2 Test Results in Outpatient Health Facilities and Emergency Departments Among Children and Adolescents Aged <18 Years — Mississippi, September–November 2020 December 18 CDC
Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study December 17 The Lancet Respiratory Medicine
Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia December 17 The New England Journal of Medicine
Racial Bias in Pulse Oximetry Measurement December 17 The New England Journal of Medicine
Patient-Reported Experiences of Discrimination in the US Health Care System December 15 JAMA
Readmission and Death After Initial Hospital Discharge Among Patients With COVID-19 in a Large Multihospital System December 14, 2021 JAMA
Household Transmission of SARS-CoV-2 A Systematic Review and Meta-analysis December 14 JAMA
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 December 11 The New England Journal of Medicine
Universal screening for SARS-CoV-2 infection among pregnant women at Elmhurst Hospital Center, Queens, New York December 10 PLOS One
Children and COVID-19: State-Level Data Report December 10 American Academy of Pediatrics
Assessment of Machine Learning to Estimate the Individual Treatment Effect of Corticosteroids in Septic Shock Dec 10 JAMA
Risk Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19 December 10 JAMA
Assessment of Racial/Ethnic Disparities in Hospitalization and Mortality in Patients With COVID-19 in New York City December 4, 2020 JAMA
Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer December 1 The New England Journal of Medicine
Antibody Cocktail for COVID-19 Gets Emergency Use Authorization November 30 Infectious Disease Advisor
Remdesivir Superior to Placebo in Hospitalized Patients With COVID-19 November 25 Infectious Disease Advisor
Association Between ABO and Rh Blood Groups and SARS-CoV-2 Infection or Severe COVID-19 Illness November 24, 2020 Annals of Internal Medicine
Surviving COVID-19 After Hospital Discharge: Symptom, Functional, and Adverse Outcomes of Home Health Recipients November 24 Annals of Internal Medicine
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia November 24 The New England Journal of Medicine
Risk factors and outcomes of hospitalized patients with severe COVID-19 and secondary bloodstream infections: A multicenter, case-control study November 20, 2020 Clinical Infectious Diseases
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia November 20, 2020 Journal of Thrombosis and Haemostasis (JTH)
SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis November 19 The Lancet
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells November 13 Cell Metabolism
Clinical Outcomes From COVID-19 Infections Poorer Among Patients with Substance Use Disorders November 16 Psychiatric Services in Advance
Low incidence of severe gastrointestinal complications in COVID-19 patients admitted to the intensive care unit: a large, multi-center study November 12 Gastroenterology
Remdesivir for the Treatment of Covid-19 — Final Report November 5 The New England Journal of Medicine
Identifying patients with symptoms suspicious for COVID-19 at elevated risk of adverse events: The COVAS score November 4 American Journal of Emergency Medicine
Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship November 2 European Journal of Clinical Microbiology & Infectious Diseases
FDA Approves First Treatment for COVID-19 October 22 FDA
CDC redefines COVID-19 close contact, adds brief encounters October 21 AP News
Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia October 20 JAMA
Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App October 21
Excess Deaths Associated with COVID-19, by Age and Race and Ethnicity — United States, January 26–October 3, 2020 October 20 CDC
Race, Ethnicity, and Age Trends in Persons Who Died from COVID-19 — United States, May–August 2020 October 16 CDC
Large Meta-analysis Digs Into Obesity’s COVID-19 Risks October 15 JAMA
A Point-Based Risk Calculator Predicting Mortality in Patients That Developed Postoperative Sepsis Journal of Intensive Care Medicine October 12
Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019 October 12 CHEST
Genomic evidence for reinfection with SARS-CoV-2: a case study October 12 The Lancet
Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March–August 2020 October 9 CDC
Transmission Dynamics by Age Group in COVID-19 Hotspot Counties — United States, April–September 2020 October 9 CDC
Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study October 8 The Lancet
Most Coronavirus-Positive Cancer Patients Are Asymptomatic, Says Study October 7 Cancer Therapy Advisor

Guideline Documents

Review guidance from countries and hospital systems that are responding to COVID-19.

NIH COVID-19 Treatment Guidelines - Last updated July 17
Surviving Sepsis Campaign COVID-19 Guidelines
Brigham and Women's Hospital COVID-19 Clinical Guidelines
Massachusetts General Hospital Department of Medicine COVID-19 Treatment Guidelines
Michigan Medicine University of Michigan COVID-19 Information and Guidelines
Nebraska Medicine COVID-19 Resources for Providers
Penn Medicine Treatment Guidelines for SARS-CoV-2 Infection
University of Washington UW Medicine COVID-19 Resources

Training to Help Staff Be Critical Care Capable

SCCM Critical Care for the Non-ICU Clinician Online Training
Critical Care for the Hospitalist Webinar Series
COVID-19 Back to the Basics: Caring for the Critically Ill Video Series
Point-of-Care Ultrasound in COVID-19 (WVU)

Resources Pages

View additional resources from organizations and societies.

Personal Protective Equipment Preservation Best Practices FEMA
CDC COVID-19 FAQ
AAFP COVID-19 Resources for Family Physicians
AAP COVID-19 Resources for Pediatricians
ACCP COVID-19 Resources CHEST
ACEP COVID-19 Resources for Emergency Physicians
ACOG COVID-19 Resources for OB/GYN
ACP COVID-19 Physician's Guide for Internists
ACS COVID-19 Resources for Surgeons and Trauma Centers
IDSA COVID-19 Resources Infectious Disease
SCCM COVID-19 Emergency Resources for Critical Care
SHM COVID-19 Resources for Hospitalists
AAPA COVID-19 Resources for Physicians' Assistants
AANA COVID-19 Resources for Nurse Anesthetists
AANP COVID-19 Recommendations for Nurse Practitioners
ANA COVID-19 Resources for Nurses
AACN COVID-19 Resources for Critical Care Nurses
APTA COVID-19 Resources for Physical Therapists
NAHC COVID-19 Resources for Home Care & Hospice
American College of Allergy, Asthma & Immunology COVID-19 Resources